Asian Journal of Pharmacy and Technology
  • Year: 2026
  • Volume: 16
  • Issue: 1

Phytosome: A Novel Drug Delivery System

1Student, Navsahyadri Instituent of Pharmacy, Pune, Maharashtra, India

2Student, Navsahyadri Instituent of Pharmacy, Pune, Maharashtra, India

3Guide, Navsahyadri Instituent of Pharmacy, Pune, Maharashtra, India

*Corresponding Author E-mail: dipalihagir5@gmail.com

Abstract

Glycerophospholipids and plant-based components combine to generate lipid-compatible compounds in phytosomes, which are innovative delivery mechanisms. "Phyto" means plant-derived, and "some" means a structure that resembles a cell. Using this novel method, phospholipids can combine with water-soluble phytoconstituents or standardised herbal extracts to form molecular complexes that improve absorption and bioavailability. By adding polyphenols to these phospholipid-based systems, the problems caused by their poor oral absorption are resolved. Phytosomes enhance gastrointestinal absorption and raise plasma concentrations of active substances by encasing hydrophilic herbal components in a lipophilic layer. The review underscores the growing function of phytosomes in augmenting the medicinal efficacy of herbal treatments and their diverse pharmaceutical formulations, including gels, pills, creams, and suspensions.

Keywords

Phytosome, Novel drug delivery system, Phospholipids, Preparation, Application, Bioavailability, Characterization etc