Asian Journal of Pharmacy and Technology

  • Year: 2014
  • Volume: 4
  • Issue: 4

Synthesis and Evaluation of Some New Imidazole Derivatives for their Anti-Microbial and Anti-Inflammatory activities

  • Author:
  • Hemlata Bhawar1,, Nachiket Dighe1, Pankaj Shinde1, Ravi Lawre2, Sanjay Bhawar3
  • Total Page Count: 6
  • DOI:
  • Page Number: 189 to 194

1Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, Maharashtra, India-413736

2Department of Quality Assurance Technique, Pravara Rural College of Pharmacy, Loni, Maharashtra, India-413736

3Department of Pharmacology, Pravara Rural College of Pharmacy, Loni, Maharashtra, India-413736

Abstract

The synthesis, structure and biological activity of Imidazole derivatives have long been the focus of research interests in the field of Medicinal Chemistry. A number of Imidazole derivatives have been reported to possess interesting biological activities such as Antimicrobial, Anti-inflammatory and Antifungal activities etc. Around 22 new derivatives were synthesized, with the standard chemicals and well established procedures. The synthesized compounds were tested for their preliminary tests, physical constants, TLC etc. IR, 1H-NMR Spectra and CHN analysis confirmed the structures of the final compounds. The proposed compounds were screened for their antimicrobial and anti-inflammatory activities with the standard drugs in the well-equipped microbiology and pharmacology lab by using standard methods.

Keywords

Anti-inflammatory, Antimicrobial and Imidazole