Asian Journal of Pharmacy and Technology
  • Year: 2017
  • Volume: 7
  • Issue: 4

Formulation and Evaluation of Controlled Release tablets of Aspirin

  • Author:
  • Chinmaya Keshari Sahoo1,, K. Satyanarayana2, D. Venkata Ramana3, Kanhu Charan Panda4
  • Total Page Count: 5
  • Page Number: 229 to 233

1Assistant Professor, Department of Pharmaceutics, Malla Reddy College of Pharmacy, Maisammaguda, Secunderabad, Telangana-500014

2Professor and Principal, Department of Pharmacognosy, Princeton College of Pharmacy, Korremula, Ghatkesar, R. R. District, Telangana-500088

3Professor, Department of Pharmaceutical Technology, Netaji Institute of Pharmaceutical Sciences, Toopranpet, Yadadri Bhongir, Telangana-508252

4Associate Professor, Department of Pharmaceutics, Anwarul Uloom College of Pharmacy, Newmallepally, Hyderabad, Telangana

*Corresponding Author E-mail: sahoo.chinmaya83@gmail.com

Online published on 2 June, 2018.

Abstract

The present work was aimed to develop controlled release tablets of aspirin. Direct compression technique was adopted for the preparation of all these formulations. The developed tablets were evaluated for pre compression parameters; post compression parameters, in vitro dissolution study. Among all the developed batches ASF3 showed highest drug release 96.14% at the end of 10 h. The optimized formulation was found to be stable up to 3 months when tested for stability study at 40±2ºC/75±5% RH.

Keywords

Aspirin, direct compression, in vitro drug release, stability study