Asian Journal of Research in Chemistry
Open Access
  • Year: 2008
  • Volume: 1
  • Issue: 1

Biological Activity of Some (2E)-Substituted-2-Ethylidene-5,6-Diphenylimidazo[2,1-b][1,3]Thiazol-3-(2H)-Ones

  • Author:
  • VH Bhaskar1,, M Kumar2, BR Balakrishnan2, B Sangameswaran2
  • Total Page Count: 3
  • Page Number: 12 to 14

1M.P. Patel College of Pharmacy, Kapadwanji, Gujarat- 387 6202

2Medicinal Plant Research Centre, Vinayaka Mission's College of Pharmacy, Vinayaka Missions University, Salem-636 008, Tamil Nadu, India

*Corresponding Author E-mail: vhbhaskar@yahoo.co.in

Online published on 13 March, 2013.

Abstract

Certain (2E)-substituted-2-ethylidene-5,6-diphenylimidazo[2,1-b][1,3]thiazol-3-(2H)-ones (4a-f) have been synthesized by the condensation of 4,5-diphenylimidazoin-2-thiones (3) with different aromatic aldehydes and chloroacetic acid in presence of acetic anhydride, anhydrous sodium acetate and glacial acetic acid. These compounds were characterized by their analytical and spectral data. The title compounds were found to be efficient antibacterial agents on evaluation.

Keywords

Imidazothiazole, Biological Activity, Antibacterial Activity