1Department of Chemistry, S. P. D.M. Art, Science, Commerce College, Shirpur – 425 405, (M.S.), India
2Department of Pharmaceutical Chemistry, Government College of Pharmacy, Amravati – 444 604, (M.S.), India
3Sai Adventerium Pharmaceutical Ltd, Hydrabad, (A.P.), India
*Corresponding Author E-mail: baviskarbhushan@gmail.com
Online published on 13 March, 2013.
Some novel chalcones were synthesized by condensation of N-(4-phenylthiazol-2-yl) acetamide with aromatic aldehydes in presence of aqueous potassium hydroxide solution at room temperature. All the title compounds characterized on the basis of their IR, 1H NMR spectroscopic data and elemental analysis. All the compounds have been screened for antimicrobial activity by the cup-plate method.
Synthesis, Thiazole, Chalcones, Aldehydes, Antimicrobial activity