Asian Journal of Research in Chemistry
  • Year: 2008
  • Volume: 1
  • Issue: 2

Design and Synthesis of Some Novel Chalcones as Potent Antimicrobial Agent

  • Author:
  • Bhagyesh Baviskar1,, Sureshbhi Patel1, Bhushan Baviskar2, SS Khadabadi2, Mahendra Shiradkar3
  • Total Page Count: 3
  • Page Number: 67 to 69

1Department of Chemistry, S. P. D.M. Art, Science, Commerce College, Shirpur – 425 405, (M.S.), India

2Department of Pharmaceutical Chemistry, Government College of Pharmacy, Amravati – 444 604, (M.S.), India

3Sai Adventerium Pharmaceutical Ltd, Hydrabad, (A.P.), India

*Corresponding Author E-mail: baviskarbhushan@gmail.com

Online published on 13 March, 2013.

Abstract

Some novel chalcones were synthesized by condensation of N-(4-phenylthiazol-2-yl) acetamide with aromatic aldehydes in presence of aqueous potassium hydroxide solution at room temperature. All the title compounds characterized on the basis of their IR, 1H NMR spectroscopic data and elemental analysis. All the compounds have been screened for antimicrobial activity by the cup-plate method.

Keywords

Synthesis, Thiazole, Chalcones, Aldehydes, Antimicrobial activity