ASIAN JOURNAL OF RESEARCH IN CHEMISTRY
  • Year: 2017
  • Volume: 10
  • Issue: 3

pH-Metric measurements of azelastine hydrochloride with Cu(II), Co(II) and Fe(II) metal ions

1Maulana Azad College of Arts, Science and Commerce, Dr. Rafiq Zakaria Campus -I, Aurangabad Pin 431001 (M.S.) India.

2Maulana Azad College of Arts, Science and Commerce, Dr. Rafiq Zakaria Campus -I, Aurangabad Pin 431001 (M.S.) India.

*Corresponding Author E-mail: faozia11365@gmail.com

**Corresponding Author E-mail: maqdoom@gmail.com

Online published on 22 September, 2017.

Abstract

Proton-ligand stability constant, metal-ligand stability constants, pK and log k of azelastine hydrochloride with Cu(II), Co (II) and Fe(II) metal ions were determined by pH-metric technique. Irving-Rossotti titration technique was used for determination of stability constants. 1:1 complexes were formed in present investigation in between azelastine hydrochloride (TH) and Cu (II), Co (II) and Fe(II) metal ions.

Keywords

Azelastine hydrochloride (AH), Stability constant, pH-metry