1Rajarshi Shahu Mahavidhyalaya, Latur, Maharashtra-413512, India
2Shivneri College, Shirur Anantpal, Dist. Latur, Maharashtra--413544, India
3Department of Chemistry, KMC College, Khopoli, Maharashtra--410203, India
4Research Laboratory for Pure and Applied Chemistry, M. M. College, Nilanga, Dist. Latur, MH, 413521, India
*Corresponding Author E-mail: amritkund_jk@rediffmail.com
Online published on 26 March, 2018.
An efficient route for the synthesis of aromatic imines has been developed using simple protocol at room temperature. The synthesis was completed by using commercially available starting material. Here we synthesized fourteen imines derivatives with excellent yield. Synthesized intermediates showed potent inhibition of Mycobacterium tuberculosis. The Schiff's bases shown drug like properties and is a good starting point for further exploration in antituberculosis drug discovery.
Schiff's bases, imines, biological activity, aldehydes, DMF
