1Department of Chemistry, KMC College, Khopoli, Maharashtra--410203, India
2Rajarshi Shahu College, Latur, Maharashtra-413512, India
3Shivneri College, Shirur Anantpal, Dist. Latur, Maharashtra-413544, India
4Research Laboratory for Pure and Applied Chemistry, M. M. College, Nilanga, Dist. Latur, MH-413521, India
*Corresponding Author E-mail: jairajdawale@gmail.com
Online published on 2 June, 2018.
An efficient route for the synthesis of aromatic hydrazones has been developed using simple protocol in water. The synthesis was completed by using commercially available starting material. Synthesized intermediates showed potent inhibition of Mycobacterium tuberculosis. The protocol shows broad substrate scope. The phenyl hydrazine shown drug like properties and is a good starting point for further exploration in antituberculosis drug discovery.
Benzophenone, hydrazine hydrate, green, drug, ethanol
