Asian Journal of Research in Chemistry

Estimation of Antibacterial efficacy in alkaloids of different parts (Root, Stem, Bark, Flower and Gum) of Anogeissus rotundifolia against some pathogenic micro-organisms (bacteria). Alkaloids extracts of all the parts of selected plant were found to possess strong antibacterial efficacy against these test pathogens, as revealed by Zone of Inhibition, Activity Index, Minimum inhibitory concentration, Minimum bactericidal concentration and Total activity of extracts against each sensitive test pathogens were also evaluated. All the pathogens were found to be sensitive against these alkaloid extracts. Alkaloid extract of the root and stem showed best activity against Bacillus subtilis (G+ve bacteria), ZOI (16.50±0.24 mm), AI (1.100), MIC (0.078 mg/ml) and MBC (0.157 mg/ml). Highest Total activity (456.410 ml/gm) of gum alkaloid was found against Bacillus subtilis. The findings of the present study suggested the exploration of alkaloid extracts of Anogeissus rotundifolia for future antimicrobial drugs.