1Rajarshi Shahu College, Latur, Maharashtra-413512, India
2Department of Chemistry, KMC College, Khopoli, Maharashtra--410203, India
3Shivneri College, Shirur Anantpal, Dist. Latur, Maharashtra-413544, India
4Research Laboratory for Pure and Applied Chemistry, M. M. College, Nilanga, Dist. Latur, MH-413521, India
*Corresponding Author E-mail: amritkund_jk@rediffmail.com
Online published on 2 June, 2018.
An efficient route has been developed for the synthesis of coumarin derivatives by green process, the ecofriendly protocol allows the reaction condition smooth. The diverse scope of salicylaldehyde has shown and synthesized intermediates showed potent inhibition of Antimicrobial activity. The synthesized derivatives characterized well by using spectroscopic techniques NMR, mass and IR analysis. This protocol allows diverse modification as well synthesis of coumarin acetamide derivatives.
Coumarin, acetamide, biological activity, reflux, modifications, synthesis