Synthesis and biological evaluation of coumarin acetamide derivatives

An efficient route has been developed for the synthesis of coumarin derivatives by green process, the ecofriendly protocol allows the reaction condition smooth. The diverse scope of salicylaldehyde has shown and synthesized intermediates showed potent inhibition of Antimicrobial activity. The synthesized derivatives characterized well by using spectroscopic techniques NMR, mass and IR analysis. This protocol allows diverse modification as well synthesis of coumarin acetamide derivatives.