Asian Journal of Research in Chemistry
  • Year: 2018
  • Volume: 11
  • Issue: 3

Synthesis and antibacterial activity of pyrazolo[5, 1-c]thieno[3, 4-e][1, 2, 4] triazin-6-Amide derivatives

  • Author:
  • V Balaraju1,2, S Yadaiah1, Ramchander Merugu1, M. Jyothi1, Laxminarayana Eppakayala2,
  • Total Page Count: 4
  • Page Number: 603 to 606

1Mahatma Gandhi University, Anneparthy, Nalgonda-508 254 (Telangana) India

2Sreenidhi Institute of Science and Technology (Autonomous), Ghatkesar, Hyderabad-501 301 (Telangana) India

*Corresponding Author E-mail: elxnkits@yahoo.co.in

Online published on 21 August, 2018.

Abstract

A series of Pyrazolo[5, 1-c]thieno[3, 4-e] [1, 2, 4]triazin-6-amide derivatives were synthesized from 5-amino pyrazole and characterized by spectral analyses and their antibacterial activity was evaluated. Compound 5a was the most active among all the compounds synthesized compared to other compounds.

Keywords

5-Amino pyrazole, 3-aminocrotononitrile, sulfur, 3-Bromopropionyl chloride, pyrazolothienotrizin