Asian Journal of Research in Chemistry
  • Year: 2018
  • Volume: 11
  • Issue: 4

Novel Synthesis of Norepinephrine Thiocarbamides

1Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati-444604, Maharashtra State, India

2Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati-444604, Maharashtra State, India

*Corresponding Author E-mail: skdtayade@gmail.com, abhijitdhande@rediffmail.com

Online published on 24 October, 2018.

Abstract

A new series of norepinephrine thiocarbamides was synthesized by the interactions of norepinephrine with ethyl and phenyl isothiocyanates in acetone medium, to isolate 1, 1-(1R)(3, 4-Dihydroxyphenyl)-2-ethylthiocarbamidoethanol [DHPETC] and 1, 1-(1R)(3, 4-Dihydroxyphenyl)-2-phenylthiocarbamidoethanol [DHPPTC] respectively. The products thus synthesized in these reactions were characterized on the basis of conventional elemental analysis, chemical characteristics and through IR, PMR, CMR and Mass spectral analysis.

Keywords

Norepinephrine, isothiocyanates, norepinephrine thiocarbamides