Asian Journal of Research in Chemistry

  • Year: 2018
  • Volume: 11
  • Issue: 4

Efficacy of Sevelamer Hydrochloride and Sevelamer Carbonate in Hyperphosphatemia Condition-A Review

Department of Chemistry (PG Biochemistry). Mount Carmel College Autonomous, Palace Road, Bangalore-560052

*Corresponding Author E-mail: shlini_p@rediffmail.com

Online published on 24 October, 2018.

Abstract

The objective of this review is Sevelamer hydrochloride and sevelamer carbonate and their role in hyperphosphatemia condition. Kidney is one of the vital organs in the human body. The function of the kidney involves purification of the blood, reabsorption of water, excretion of waste, secretion of hormones like adrenaline. When the kidney becomes non-functional, it leads to a condition called chronic kidney disease (CKD), where the kidney fails to purify the blood. Sevelamer is a phosphate binder that is given as a medication to treat hyperphosphatemia in patients suffering from chronic kidney disorder. It binds to the dietary proteins and prevents the absorption of the same in the body.

Keywords

Sevelamer hydrochloride, sevelamer carbonate, hyperphosphatemia, chronic kidney disease, adrenaline