A Comprehensive report on Solid Dispersions by Factorial Design

The drugs of present use are lipophilic. Hence there is a need to surge the solubility of these drugs. To encounter this necessity one of the approaches is the formulation of drugs in form of Solid dispersions. Solid dispersions are a type of dispersion having one or extra one API in a torpid carrier at a solid state. We focused on the importance of solid dispersions in pharmaceutical formulation by using factorial design as it was easy to formulate. These solid dispersions are organized by several practises such as solvent technique, supercritical fluid technique and kneading tactic, etc., by referring the several journals, literature and pharmacy magazines we came to know that Solid dispersion are used to improve the solubility of the poor water-soluble drugs and also its bioavailability. At last, we conclude that through these Solid dispersions we can boost the Therapeutic efficiency of hydrophobic drugs by achieving greater solubility.