Research Department of Chemistry, Bioactive Organic Molecule Synthetic Unit, C. Abdul Hakeem College (Autonomous), Melvisharam – 632 509, Affiliated to Thiruvalluvar University, Vellore, Tamil Nadu, India
*Corresponding Author E-mail: mansoorcah@gmail.com
Online Published on 13 February, 2024.
A simple approach for the one-pot multicomponent synthesis of 4-aryl-4,5-dihydro-1H-indeno[1,2-b]pyridines is described via the condensation of 1,3-indanedione, β-ketoesters, ammonium acetate and various aromatic aldehydes in the presence of Chitosan as an environmentally benign eco‐friendly catalyst. Furthermore, excellent yields, solvent-free condition, easy work-up protocol, reusability of the catalyst and mild reaction conditions are the advantages of this method.
Chitosan, 1,3-indanedione, Multicomponent reaction, Indeno[1,2-b]pyridine, Solvent-free condition
