Department of Pharmacology, YSPM’s Yashoda Technical Campus, Satara, Maharashtra, India
The purpose of research was to establish whether an ethanolic extract of
Ethylene glycol-induced urolithiasis: For 28 days, an oral dose of 0.75% v/v ethylene glycol was given to induce urolithiasis. The animals were split up into six groups, each with six animals. For 28 days, Group I animals were administered with distilled water. For a period of 28 days, drinking water containing 0.75% v/v ethylene glycol was given to all groups except group I. Group III animals (standard group) were given 500mg/kg of Cystone from the 15th to the 28th day, Group IV, V, and VI were given oral doses of 50, 100, and 200mg/kg of
In this model, the animals were split into six groups, each consisting of six animals. Group I animals (control group) were administered with distilled water. Group II was given sodium oxalate (70mg/kg i.p.) as a lithiatic control. Group III animals were administered with 500mg/kg of the standard drug Cystone. Groups IV, V, and VI animals were administered
The outcome showed that, in comparison to lithiatic control rats, the ethanolic extract of
By inhibiting kidney crystal deposition, the ethanolic extract of
Ethylene glycol, Sodium oxalate, Urolithiasis, Bryophyllum pinnatum, Kidney
