Asian Journal of Research in Chemistry
  • Year: 2024
  • Volume: 17
  • Issue: 4

1,3,4- Oxadiazole, A Complete Review on Biological Activities of Newly Synthesized Derivatives

  • Author:
  • Amisha Bhopatrao*, Pooja Chavan, Hritisha Chavan, Pravin Chaudhari, Zahra Dadan, Ajay Kharche
  • Total Page Count: 7
  • Published Online: Aug 8, 2025
  • Page Number: 243 to 249

Konkan Gyanpeeth Rahul Dharkar College of Pharmacy and Research Institute, Karjat, 4020, India

*Corresponding Author E-mail: amishabhopatrao@gmail.com

Online Published on 08 August, 2025.

Abstract

1,3,4-oxadiazole scaffold is reported to show various biological activities like anticancer, anti-inflammatory, antimicrobial, analgesic, anticonvulsant and many more. Many derivatives containing basic moiety as 1,3,4-oxadiazole was useful against different human cell lines causing cancer. There are some derivatives which were tested for their anti-inflammatory potential using rat paw edema method. Some novel derivatives were showing their antimicrobial activity against various microbes. Also newly synthesized compounds were reported for their better analgesic and anticonvulsant potential than the reference drug during testing. This review describes biological activities of recently synthesized novel derivatives containing 1,3,4-oxadiazole moiety with structures.

Keywords

Oxadiazoles, 1,3,4-Oxadiazol, Antimicrobial activity, Analgesic activity