Importance of GC-MS for Analyzing Sars-Cov-2 Drugs in Biological Sample

The advent way of the SARS-CoV-2 virus has put a lot of pressure on the actual way of developing drugs and diagnostics. Gas Chromatography-Mass Spectrometry (GC-MS) is rapidly becoming one of the most valuable techniques in detecting and identifying drugs related to COVID-19 in biological samples. This method integrates the separation capabilities of gas chromatography with the identification power of mass spectrometry, enabling the analysis of volatile and semi-volatile compounds. Through GC-MS, researchers can identify trace elements in complex biological matrices, such as serum, urine, and exhaled breath, which is crucial for monitoring drug concentrations and understanding pharmacokinetics. Notably, GC-MS has been instrumental in detecting antiviral drugs like chloroquine and hydroxychloroquine, as well as identifying volatile biomarkers associated with COVID-19 infection. The application of GC-MS extends beyond drug analysis; it also plays a significant role in early diagnosis by analyzing breath samples for specific metabolites linked to SARS-CoV-2. This paper discusses the importance of GC-MS in SARS-CoV-2 research, highlighting its applications in drug detection, early diagnosis, and public health management.