Pharmaceutical Standardization and Analytical Evaluation of Drakshavaleha

Ayurveda emphasizes formulations that ensure efficacy, palatability and stability. Bhaishajya Kalpana, the pharmaceutics branch of Ayurveda, provides systematic methods of preparing dosage forms. Among these, Avaleha Kalpana represents a semisolid preparation prepared with decoctions or expressed juices and sweetened with jaggery, sugar or honey. Drakshavaleha is a classical formulation described in Ashtanga Hridaya under Pandu Chikitsa prepared with Draksha, Amalaki and other supportive herbs. It is therapeutically indicated in Pandu (Anemia), Kamala (Jaundice) and liver disorders. Materials and Methods: The pharmaceutical process involved soaking and deseeding Draksha, extracting Amalaki Swarasa, preparing Prakshepaka Churna, and formulating Drakshavaleha with incorporation of Prakshepaka Dravya and honey. Classical Avaleha SiddhiLakshana’s were observed to determine the endpoint. Analytical evaluation included organoleptic, physicochemical and phytochemical analyses along with HPTLC as per the Ayurveda Pharmacopoeia of India. Parameters assessed were loss on drying, extractive values, pH, fat content, total acidity, ash values, sugar content, and qualitative phytochemical tests. Results: The final product was a dark brown semisolid Avaleha with characteristic odor and sweet-pungent taste. Organoleptic properties were uniform across batches. Physicochemical analysis showed LOD (19.32–21.93%), water-soluble extractive (69.6–74.8%), alcohol-soluble extractive (72–74%), total acidity (2.59–2.61mEq/g), pH (3.05–3.11), fat (0.07–0.27 %), total ash (2.8–3.09%), total sugar (48.96–51.13%) and reducing sugar (44.15–47.91%). Phytochemical screening confirmed the presence of carbohydrates, steroidal glycosides, tannins, and flavonoids. HPTLC profiling of all batches confirmed consistent phytoconstituent presence, ensuring batch uniformity and standardization. Conclusion: Draksha valeha was successfully prepared and standardized through pharmaceutical and analytical evaluation. The results confirmed its quality, stability, and reproducibility as a classical Avaleha formulation.