Asian Journal of Research in Chemistry
  • Year: 2009
  • Volume: 2
  • Issue: 1

Synthesis and Biological Evaluation of 2, 5 Di-substituted 1, 3, 4 oxadiazoles

  • Author:
  • Rakesh Saini1,, Awani K Rai1, AN Kesari1, M Shahar Yar2
  • Total Page Count: 3
  • Page Number: 34 to 36

1Department of Pharmacy, Pranveer Singh Institute of Technology, kalpi road, bhauti, Kanpur-208020, Uttar Pradesh, India

2Department of Pharmacy, Jamia Hamdurd, New Delhi

*Corresponding Author E-mail: rakeshpsit.saini@gmail.com

Online published on 13 March, 2013.

Abstract

Synthesis of (ethyl 2-(1H Benzo [d] [1, 2, 3] triazole –1-yl] acetate) and (2H – benzo [d] [1, 2, 3] triazole – 1 – yl aceto hydrazine) alongwith their derivatives has been done. The entire synthesized compounds were characterized by UV, IR and 1H-NMR specteoscopy. The Antimicrobial activity of the synthesized compounds was evaluated, on Sreptococcus aureus and Esteria coli. The present investigation deals with the synthesized compounds possessing good antimicrobial activity.

Keywords

Esterification, Benztriazole, Antimicrobial activity