Asian Journal of Research in Chemistry
  • Year: 2009
  • Volume: 2
  • Issue: 1

Antidiabetic potential of aqueous and alcoholic leaf extracts of Pithecellobium dulce

  • Author:
  • M Sugumaran1,, T Vetrichelvan1, S Darlin Quine2
  • Total Page Count: 3
  • Page Number: 83 to 85

1Adhiparasakthi College of Pharmacy, Melmaruvathur-603319

2School of Chemical and Biotechnology, SASTRA University, Thanjavur-613402

*Corresponding Author E-mail: murugesansugumaran@yahoo.com

Online published on 13 March, 2013.

Abstract

Ethanolic and aqueous leaf extract of Pithecellobium dulce was studied for its antidiabetic activity using streptozotocin-induced diabetic model in rats. The aqueous extract showed significant activity (P<0.01) than the alcoholic extract at the tested dose level which was comparable to glibenclamide, a standard antidiabetic drug. HPTLC fingerprinting profile of the aqueous extract was also developed which would serve as reference standard for quality control of this extract.

Keywords

Alloxan, Anti-diabetic, Leaf extracts, Pithecellobium dulce