The present research work discusses the development of a UV estimation method for Idebenone. Simple, accurate, cost efficient and reproducible spectrophotometric method has been developed for the estimation of Idebenone in bulk and pharmaceutical dosage form. UV spectrophotometric method, which is based on measurement at maximum wavelength (λmax) 282nm. The percentage recovery of Idebenone ranged from 99.68 to 99.82% in pharmaceutical dosage form. Beers law was obeyed in the concentration range of 4–20μg/ml having line equation y = 0.0485x -0.0239 with correlation coefficient of 0.9978. Results of the analysis were validated statistically and by recovery study.
UV spectrophotometry, Idebenone
