K. M. Kundnani College of Pharmacy, Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Colaba, Mumbai-400 005, India
*Corresponding Author E-mail: phalemitesh@gmail.com
Online published on 13 March, 2013.
The analytical industry today is showing a serious shift in the paradigm worldwide with advancements in technological compatibility and integration. Traditional analytical approaches including HPLC (High-Performance Liquid Chromatograph), GC (Gas Chromatograph), UV (Ultraviolet) detection, etc., have become insufficient to effectively address the growing number of challenges in analyses of species-specificity and sensitivity. This has given rise to investigate and offer highly advanced hyphenated techniques that meet the needs of high-technology oriented applications. Hyphenation -linking together of "standard" analytical techniques -generally leads to enhanced analytical performance. The biggest advantage of hyphenated speciation techniques is the ability to detect species other than the pre-conceived compounds. The advancement of analytical techniques is thus bringing a new era of development which will serve as a rapid and unambiguous tool in the drug development process.
HTLC, OPLC, GC-MS, GC-IR, LC-MS, LC-MS/MS