1Dept of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni 413713, India
2Dept of Pharmacology, J.N Medical College, Belgaum, India
3Dept of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, Loni 413713, India
4Dept of Pharmacology, Pd. Dr. Vitthalrao Vikhe Patil College of Pharmacy, Ahmednagar, India
A new series if substituted 1, 4-Dihydropyridine derivatives were synthesized and the structures of these compounds were established on the basis of spectral and elemental analysis. All the compounds were evaluated for anti-inflammatory activity by paw edema, xylene induced ear edema and cotton wool granuloma methods. Compounds C4, C5, C6, C7 and C9 have been found to exhibit excellent anti-inflammatory activity.
1,4-Dihydropyridine, anti-inflammatory, CHN analysis
