1Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003
2Enzene Biosciences Pvt. Ltd., Bangalore
Online published on 13 March, 2013.
An improved method for the synthesis of bicyclic pyrrolidines utilizing microwave-assisted synthesis is described. The synthesis involves microwave irradiation of an amine, aldehyde and maleimide in one pot fashion to give the desired product. The synthesized compounds were evaluated for their antibacterial activity against ciprofloxacin.