Microwave Assisted Synthesis and Antibacterial Activity of Some Bicyclic Pyrrolidines

An improved method for the synthesis of bicyclic pyrrolidines utilizing microwave-assisted synthesis is described. The synthesis involves microwave irradiation of an amine, aldehyde and maleimide in one pot fashion to give the desired product. The synthesized compounds were evaluated for their antibacterial activity against ciprofloxacin.