Asian Journal of Research in Chemistry
  • Year: 2009
  • Volume: 2
  • Issue: 4

Microwave-Assisted Synthesis and Antibacterial Activity of Some New Flavones and 1, 5-Benzothiazepines

  • Author:
  • VA Navale, SS Mokle, Archana Y Vibhute, KG Karamunge, SV Khansole, SB Junne, YB Vibhute
  • Total Page Count: 4
  • Page Number: 472 to 475

P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded 431602 (M.S.) INDIA

*Corresponding Author E-mail: drybv@rediffmail.com

Online published on 13 March, 2013.

Abstract

The synthesis of heterocyclic compounds containing flavones (4a-i) and 1,5-benzothiazepines (5a-i) from chalcone derivatives containing 3,4-methylenedioxy phenyl ring using microwave irradiation in 80–97% yield within 2 – 4 min. The work-up is simple, shorter reaction time, increase in reaction rate with better yields. The structures of synthetic compounds have been characterized using IR and 1H NMR spectral data together with halogen analysis. All synthesized compounds have been screened for their antibacterial activity.

Keywords

Chalcones, flavones, 1,5-benzothiazepines, microwave irradiation, antibacterial activity