Physio-Chemical investigation and Wound healing activity of Sesame oil and Formulated oil

Formulated oil a Siddha formulation was developed using two plant drugs namely Pongamia pinnata seeds and Boerhaavia diffusa roots. Preliminary physio chemical screening was performed in both the plants. The wound healing activity was studied with comparison of Sesame oil and Formulated oil by using standard nitro furazone ointment. The methods used were Excision wound model, Incision wound model and Dead space wound model. In excision and incision wound model the formulated oil treated group showed much greater increase in the tensile strength when compared to the control, which was almost similar to that of nitro furazone. In the dead space wound model both the sesame oil and formulated oil produced a significant increase in the wet granuloma tissue weight as well as in the dry weight.Tensile strength was also found to be increased (P<0.001) in both of the oil treated groups.