Asian Journal of Research in Chemistry
  • Year: 2009
  • Volume: 2
  • Issue: 4

Syntheses, Characterization and Biological Screening of Some Novel 1, 2, 4-Triazoles

  • Author:
  • Ram Janam Singh1,2,, Dharmendra Kumar Singh2
  • Total Page Count: 3
  • Page Number: 536 to 538

1Quality Control Laboratory, Indian Oil Corporation Limited, Panipat Refinery, Panipat, Haryana-132140 (India)

2Synthetic Research Laboratory Department of Chemistry, Faculty of Science, Tilak Dhari Post Graduate College, Veer Bahadur Singh Purvanchal University, Jaunpur, Uttar Pradesh-222002 (India)

*Corresponding Author E-mail: singhram@iocl.co.in

Online published on 13 March, 2013.

Abstract

A series of 3-alkylthio-5-pyridyl-1, 2, 4-triazoles were prepared as possible biological active agents. All the title compounds were characterized on the basis of IR, PMR, Mass spectra and elemental analyses. All compounds carring alky substituents at position three and the 1, 2, 4-triazole moiety at position one or two showed reasonable antiinflammatory activity.

Keywords

1,2,4-triazole, 1-picolinoylthiosemicarbazides, alkylation, anti-inflammatory activity