Asian Journal of Research in Chemistry
  • Year: 2010
  • Volume: 3
  • Issue: 1

Synthesis and Antioxidant Activity of Some Flavone Derivatives

  • Author:
  • Chandrahas N Khobragade1,, Ragini G Bodade1, Anand V. Manwar2
  • Total Page Count: 3
  • Page Number: 139 to 141

1School of Life Sciences, Swami Ramanand Teerth Marathawada University, Nanded-431606, India

2Department of Microbiology, Dyanopasak Mahavidyalaya, Parbhani -431401, India

*Corresponding Author E-mail: cnkhobragade@rediffmail.com

Online published on 13 March, 2013.

Abstract

Some novel flavones were synthesized by condensation reactions of substituted ketones with substituted aldehydes to form chalcones. The formed 2-hydroxyl substituted chalcone made to react with polyethylene glycol-400 (PEG-400) with catalytic amount of iodine, produces flavone derivatives. The synthesized derivatives were characterized by spectral analysis and revealed to be therapeutically active as antioxidant agents.

Keywords

Synthesis, Flavones, Antioxidant activity