1Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur-522 002
2Department of Chemistry/Pharmacy, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur-522 510
*Corresponding Author E-mail: profbsyamsundar@yahoo.co.in
Online published on 13 March, 2013.
A new simple, sensitive, precise, accurate and economical UV spectrophotometric method of analysis for almotriptan malate both as a bulk drug and in tablet formulations was developed and validated. The method employed methanol as solvent and the drug shows maximum absorbance at 227 nm with molar absorptivity of 0.8532×105 L/mol.cm. The linear regression analysis data for the calibration plot showed good linear relationship with r2 = 0.9999 in the concentration range of 1–5 μg/ml. Results of analysis were validated statistically and by recovery studies
Almotriptan malate, U.V spectrophotometry, tablets
