Asian Journal of Research in Chemistry
  • Year: 2010
  • Volume: 3
  • Issue: 1

An Efficient One Pot Synthesis of Substituted Derivatives of Pyrimido Benzothiazole

  • Author:
  • Vijay N Bhosale1,, Sambhaji P Vartale1, Sarla N Kalyankar1, Jagannath S Jadhav2, Sharad V Kuberkar1
  • Total Page Count: 5
  • Page Number: 161 to 165

1P. G. Department of Organic Chemistry, Yeshwant Mahavidyalaya, Nanded-431602, India

2Department of Organic Chemistry, N.S.B. College, Nanded-431605, India

*Corresponding Author E-mail: bhosalevn@rediffmail.com

Online published on 13 March, 2013.

Abstract

8-Chloro–3-cyano – 2 -methylthio – 4 -oxo -4[H] -pyrimido -[2,1-b] [1,3] benzothiazole has been prepared by the reaction of 6-Chloro-2-amino benzothiazole with ethyl-2-cyano-3,3-bismethylthioacrylate in the presence of diemethyl formamide and anhydrous potassium carbonate. Suspectibility of compound towards condensation with different reagents like aryl amines, heteryl amines, phenols and compound containing active methylene group has been investigated.

Keywords

8-Chloro–3-cyano – 2 -methylthio – 4 -oxo -4[H] -pyrimido -[2,1-b] [1,3] benzothiazole, ethyl-2-cyano-3,3-bismethylthioacrylate