Synthesis and Analgesic Activity of 2, 5 Di-Substituted 1, 3, 4 Oxadiazoles

1, 2, 3 benzotriazole derivative also show several pharmacological activities viz.example. Antimicrobial activity, Anti inflammatory, Anti analgesic activity, Anticancer etc. On the basis of our observation the parent research work was carried out to synthesize 1, 2, 3 triazole substituted 1, 3, 4 oxadiazoles and to further evaluate Analgesic activity. Synthesis of (ethyl 2-(1H Benzo [d] [1, 2, 3] triazole –1-yl] acetate) and (2H – benzo [d] [1,2,3] triazole – 1 – yl aceto hydrazine) along with their derivatives has been done. The entire synthesized compounds were characterized by UV, IR and ¹H-NMR specteoscopy. The Antimicrobial activity of the synthesized compounds was evaluated, on albino rats. The present investigation deals with the synthesized compounds possessing good Analgesic activity.