Asian Journal of Research in Chemistry
  • Year: 2010
  • Volume: 3
  • Issue: 2

Synthesis and Antimicrobial Activity of 5-Substituted-2-(1-H-Benzimidazole) Sulfonamides

  • Author:
  • YS Rane, RR Varma, LS Patil, SV Athlekar, AS Chowdhary, AS Bobade
  • Total Page Count: 4
  • Page Number: 335 to 338

Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel Mumbai -12

*Corresponding Author E-mail: yora_03@yahoo.com, rajeevvarma84@gmail.com

Online published on 13 March, 2013.

Abstract

Heterocyclic compounds such as 5-substituted-2-(1-H-benzimidazole) sulfonamides were synthesized by condensation of 5-substituted-2-(1-H-benzimidazole)-sulfonyl chloride and 2-aminoheterocycles with triethyl amine in dry acetone. The synthesized compounds were checked for their antimicrobial potency by screening them against two bacterial strains as well as one fungal strain. The structures of compounds have been established on the basis of their elemental analysis and spectral data.

Keywords

Sulphonamides, 2-mercapto benzimidazole, antifungal, antibacterial