Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management, Dr. Akhilesh Das Nagar, Sector 1, Faizabad Road, Lucknow, Pin-227105 (UP), India
*Corresponding Author E-mail: pj_abrol@yahoo.com
Online published on 13 March, 2013.
A series of 5-substituted-arylidene-3-substituted-benzyl-thiazolidine-2, 4-dione derivatives were synthesized from thaizolidinedione and substituted benzyl chloride followed by the addition of substituted aromatic aldehydes. All the compounds 1(a)-1(e) and 2(a)-2(c) were screened for their in vitro antioxidant activity using DPPH method. The anisaldehyde based thiazolidinedione compounds 1(a) and 2(a) displayed good activity comparable to those of standard.
Thiazolidine-2,4-dione, Heterocyclic compounds, Antioxidant activity
