Nanodrop Spectrophotometric Method for Estimation of Ranitidine Hydrochloride in Bulk and Tablet Dosage Form

A novel, simple, sensitive and rapid nanodrop spectrophotometric method was developed for the estimation of Ranitidine hydrochloride in bulk and its pharmaceutical tablet dosage form. Ranitidine hydrochloride exhibiting maximum absorbance at 316 nm in distilled water and obeyed linearity in the concentration range of 5–100 ppm. The proposed method has been applied successfully for the analysis of Ranitidine hydrochloride either in bulk or pharmaceutical tablet dosage form with good accuracy and precision. The method herein described can be employed for quality control and routine analysis of Ranitidine hydrochloride in pharmaceutical tablet dosage form.