Asian Journal of Research in Chemistry
  • Year: 2010
  • Volume: 3
  • Issue: 4

Conventional and Microwave-assisted Synthesis of 5-Halogeno-(X) 2, 4-(1H, 3H) Pyrimidinedione and Their Biological Evaluation

  • Author:
  • Shahana Ehsan, Bushra Khan
  • Total Page Count: 4
  • Page Number: 1103 to 1106

Chemistry Department Lahore College for Women University, Jail Road, Lahore, Pakistan

*Corresponding Author E-mail: shahana_organic@hotmail.com

Online published on 13 March, 2013.

Abstract

A series of 5-halogen substituted 2, 4-(1H, 3H) Pyrimidinedione compounds have been synthesized by an effective, rapid microwave assisted method. The structures of compounds have been elucidated with UV, FTIR, GC-Mass spectrometer, solubility and melting points of compounds were determined. The antibacterial, antifungal and antiviral screening against B.subtilis, S.aureus, E.coli, A.nigar, A.flavus and ND virus revealed their significant activities.

Where, X = F, Cl, Br, I

Keywords

Pyrimidinedione, Halogenation, Superoxol, Microwave