Asian Journal of Research in Chemistry
  • Year: 2011
  • Volume: 4
  • Issue: 1

Anti-Oxidant Activity of Novel 5-Substituted Arylidene-3-SubstitutedBenzyl-Thiazolidine-2, 4-Diones

  • Author:
  • Sachin Malik, Ashish Choudhary
  • Total Page Count: 3
  • Page Number: 120 to 122

Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management, Lucknow 227105 (UP), India

*Corresponding Author E-mail: pr.sachinmalik@gmail.com

Online published on 6 March, 2013.

Abstract

A series of 5-substituted-arylidene-3-substituted-benzyl-thiazolidine-2, 4-dione derivatives were synthesized from thaizolidinedione and substituted benzyl chloride followed by the addition of substituted aromatic aldehydes. All the compounds 1(a)-1(e) and 2(a)-2(c) were screened for their in vitro antioxidant activity using DPPH method. The anisaldehyde based thiazolidinedione compounds 1(a) and 2(a) displayed good activity comparable to those of standard.

Keywords

Thiazolidine-2, 4-dione, Heterocyclic compounds, Antioxidant activity