1Tallapadmavathi College of Pharmacy, Urus, Kareemabad, Warangal, A.P, India
2Trinity College of Pharmaceutical Sciences, Peddapalli, Karimnagar, A.P, India
3Balaji Institute of Pharmaceutical Sciences, Narsampet, Warangal, A.P, India
*Corresponding Author E-mail: drarunadevi.tcps@gmail.com
Online published on 6 March, 2013.
Seven different 2-[(1H-benzimidazol-2yl methyl) sulfanyl)] –N4-(phenylmethylidene) acetohydrazides were synthesized from 2-[(1H-benzimidazol-2-yl methyl) sulfanyl] acetohydrazide on reaction with different aromatic aldehydes in methanol. Each of these compounds were purified and characterized by their spectral data. All the compounds were assayed for their anti-inflammatory activity by carrageenan induced rat hind paw edema method. Some of these compounds showed moderate to considerable anti-inflammatory activity.
Benzimidazol-2-methane thiol derivatives, aromatic aldehydes, anti-inflammatory activity
