Asian Journal of Research in Chemistry

  • Year: 2011
  • Volume: 4
  • Issue: 10

Synthesis, Spectroscopic, Thermal Characterization and Biological Activity of (E)-4-(4-Methoxybenzylideneamino)-N-(5-Methylisoxazol-3-Yl) Benzenesulfonamide and Its Copper Complexes.

  • Author:
  • M. Elnawawy, R.S. Farag, I.A. Sbbah, A.M. Abuyamine
  • Total Page Count: 4
  • DOI:
  • Page Number: 1578 to 1581

Faculty of Science, Al-Azhar University, Cairo, Egypt

Abstract

A Schiff base (E)-4-(4-methoxybenzylideneamino)-N-(5-methylis-oxazol-3-yl) benzene-sulfonamide (C18H17N3O4S), and its copper complex were synthesized and the structures elucidated in the bases of elemental analysis, 1HNMR, UV–VIS, IR, Mass spectroscopy, magnetic susceptibility, thermal analysis and conductance measurements. The studies indicate an octahedral structure for the complexes with the (C22H27N3O10SCu) formula. The I.R. spectra suggest that the ligand acts as a tridentate (NNO) donor. Also, the biological activity of the Schiff base and its Cu complex are biologically active.

Keywords

sulphamethoxazole, Schiff base, copper complex, antibacterial, antifungal activities