1Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, Maharashtra, India-413736
2Department of Pharmaceutical Chemistry, R.G.Sapkal College of Pharmacy, Nashik, M.S., India
3Department of pharmaceutical Chemistry, S.N.D. College of Pharmacy, Yeola, Dist-Nashik, Maharashtra, India
4Department of Pharmaceutical Sciences and Research, Bhagwant University, Ajmer, Rajasthan, India
*Corresponding Author E-mail: nachiket1111@rediffmail.com
Online published on 6 March, 2013.
Triazole is a five membered heterocyclic system consisting of two carbon atoms and three nitrogen atoms shows wide range of biological activities. Triazoles can be synthesized using Einhorn-Brunner reaction or the Pellizzari reaction from acyl hydrazides. Triazoles posses wide spectrum of biological activities like including antibacterial, antifungal, antiviral, anti-inflammatory, anticonvulsant, antidepressant, antihypertensive, analgesic, and hypoglycemic properties. The present reviews attempted to gather the various developments in synthesis and biological activities of triazole derivatives.
1,2,4-Triazole, Pharmacological activity, SAR, Total synthesis
