Synthesis, Characterization and Anti-Microbial Evaluation of Derivative of Chalcone

To development of antimicrobial agents a series of chalcones were prepared by condensation of appropriate acetophenones with different aromatic aldehyde in the presence of alkali at 37°C. The synthesized compounds were characterized by IR, NMR spectral studies. The synthesized compounds were evaluated for anti-bacterial activity, and anti-fungal activity. The result had shown that anti-bacterial and anti-fungal activity of Compound containing electron withdrawing group (G2, G4, and G6).