Asian Journal of Research in Chemistry
  • Year: 2011
  • Volume: 4
  • Issue: 2

Assay of Tolperisone by Extractive Spectrophotometry

  • Author:
  • K. Raghavi, M. Shaiba, V. Jagathi, M. Sindhura, R. Prashanthi
  • Total Page Count: 2
  • Page Number: 244 to 245

K.V. S. R. Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India

*Corresponding Author E-mail: msindhu44@gmail.com

Online published on 6 March, 2013.

Abstract

Two simple and sensitive visible spectrophotometric methods have been developed for the estimation of Tolperisone in pure and pharmaceutical dosage forms. Method A is based on co-ordinate complex formation between the drug and cobalt thiocynate (630 nm) and method B is based on charge transfer complex formation between drug and 2,3 di-chloro-5-6-dicyano 1–4,benzoquinone (DDQ 430 nm). The absorbance are measured against the corresponding reagent blanks. The methods have been statistically evaluated and found to be precise and accurate.

Keywords

Spectrophotometry, Tolperisone