1Health Care and Science, Thomson Reuters, India
**Corresponding Author E-mail: renuka1020@yahoo.co.in
**D.No: 27-5-10/1, Sreerampuram, Bhimavaram, 534202.
Online published on 6 March, 2013.
The article is a summary of the medicinal and biological significance of the most important pharmacophore among the heterocycles having many biological activities, the Isoxazole. The isoxazole is a highly active scaffold exhibiting a wide variety of medicinal and biological activities. An attempt is made in this article to cover medicinally active compounds along with the recent discoveries, which were reported to posses various biological activities. This might be helpful in developing the novel lead molecules to potential drug candidates
Hetrocycles, isoxazoles, scaffold, medicinal significance, biological significance