1Yinayaka Mission College of Pharmacy, Salem-636008, Tamilnadu, India
2SRM College of Pharmacy, Kattankulathur-603203, Tamilnadu, India
*Corresponding Author E-mail: anandbabu23@rediffmail.com
Online published on 6 March, 2013.
A new, simple, accurate and sensitive UY -spectrophotometric absorption correction method has been developed for simultaneous determination of amlodipine besylate and olmesartan medoxomil in combined tablet dosage form. Methanol and distilled water were used as solvents. The wavelengths selected for the analysis were 363nm and 258 nm for amlodipine besylate and olmesartan medoxomil, respectively. Beer's law obeyed the concentration range of 1.25 - 6.25 μg/ml and 5 -25 μg/ml for arnlodipine besylate and olmesartan medoxomil respectively. The method was validated stastically.
Amlodipine Besylate, Olmesartan medoxomil, Absorption correction method, ICH guidelines
