Asian Journal of Research in Chemistry
  • Year: 2011
  • Volume: 4
  • Issue: 7

Spectrophotometric Determination of Mosapride Citrate in Pharmaceutical Formulations

  • Author:
  • M. Purushotham Reddy1,, P. Ravindra Reddy2, N. Rami Reddy3
  • Total Page Count: 3
  • Page Number: 1161 to 1163

1Department of Chemistry, Government College for Men, Kurnool-518002, India

2Department of Chemistry, S. K. University, Anantapur-515003, India

3Department of Chemistry, S.B.S.Y.M. Degree College, Kurnool-518218, India

*Corresponding Author E-mail: mpreddy50@g.mail.com

Online published on 6 March, 2013.

Abstract

A simple spectrophotometric method has been developed for the estimation of mosapride in tablet formulations. The method is based on the formation of a orange coloured azo product by the diazotization of mosapride followed by a coupling reaction with resorcinol. The absorbance of orange coloured solution is measured at 470 nm against reagent blank. Beer's law is obeyed in the concentration of 20–100 μg/ml of drug. The method is successfully employed for the determination of mosapride in tablets formulations.

Keywords

Spectrophotometry, mosapride citrate, resorcinol, diazotization Formulations