1Department of Chemistry, Government College for Men, Kurnool-518002, India
2Department of Chemistry, S. K. University, Anantapur-515003, India
3Department of Chemistry, S.B.S.Y.M. Degree College, Kurnool-518218, India
*Corresponding Author E-mail: mpreddy50@g.mail.com
Online published on 6 March, 2013.
A simple spectrophotometric method has been developed for the estimation of mosapride in tablet formulations. The method is based on the formation of a orange coloured azo product by the diazotization of mosapride followed by a coupling reaction with resorcinol. The absorbance of orange coloured solution is measured at 470 nm against reagent blank. Beer's law is obeyed in the concentration of 20–100 μg/ml of drug. The method is successfully employed for the determination of mosapride in tablets formulations.
Spectrophotometry, mosapride citrate, resorcinol, diazotization Formulations