Dept. of Pharmaceutical Chemistry, PES College of Pharmacy, Bangalore -560050, India
*Corresponding Author E-mail: bhattacharjee.shivaji@gmail.com
Online published on 7 February, 2013.
The novel 2-amino-N-(o-fluorophenylcarboxamido)-4-(p-methoxyphenyl)-thiophene [I] was synthesized by using a pioneer method and the parent compound [I] was reacted with different substituted aryl aldehydes to obtain a series of title compounds [I a-l]. All the new title compounds were characterized by spectral data and were screened for Antimicrobial activity.
In conclusion, it can be inferred that the electron donating groups on the phenyl ring at R of the title compounds influenced the Antimicrobial activity.
Synthesis, Thiophene, Schiff Base, Characterization, Antimicrobial activity
