(N′-(pyridin-2-yl)methylene)nicotino hydrazide complexes with Mn(II), Co(II), Ni(II) and Cu(II): Synthesis, characterization and antimicrobial studies

A new series of Schiff base derived from isonicotinic acid hydrazide [INH] and pyridine-2-carbaxaldehyde [py-2-yl] transition metal complexes have been synthesized and characterized by elemental analysis, infrared, electronic spectra, thermal analyses, and magnetic susceptibility measurements. From the data obtained the molecular formula of the complexes were proposed as [M(II)((N′-(pyridin-2-yl) methylene) nicotino hydrazide)2] where M = Mn(II), Co(II), Ni(II) and Cu(II). All the complexes were found to be octahedral geometry where the Schiff base ligand act as a tridentate ligand. Antimicrobial activity against several microbes have been tested and found Co(II), Ni(II) and Cu(II) complexes exhibited potent antibacterial activity with the reference standard ciprofloxacin.