Asian Journal of Research In Chemistry
  • Year: 2012
  • Volume: 5
  • Issue: 3

A Simple UV Spectrophotometric Method Development and Validation for Estimation of Ciprofloxacin Hydrochloride in Bulk and Tablet Dosage Form

  • Author:
  • Singh Kumar Rakesh1,, Patel Singh Pankaj1, Singh Amar1, R.K. Roy2
  • Total Page Count: 4
  • Page Number: 336 to 339

1KNGD Modi Institute of Pharmaceutical Education and Research, Modinagar, U. P.-201204

2Dr. K. N. Modi Institute of Pharmaceutical Education and Research, Modinagar, U. P.-201204

*Corresponding Author E-mail: rakeshbluebalance@gmail.com

Online published on 7 February, 2013.

Abstract

A novel, simple, sensitive and rapid UV Spectrophotometric method was developed for the estimation of Ciprofloxacin hydrochloride in bulk and its pharmaceutical tablet dosage form. Ciprofloxacin hydrochloride exhibiting maximum absorbance at 274 nm in distilled water and obeyed linearity in the concentration range of 2–10 ppm. The proposed method has been applied successfully for the analysis of Ciprofloxacin hydrochloride either in bulk or pharmaceutical tablet dosage form with good accuracy and precision. The method herein described can be employed for quality control and routine analysis of Ciprofloxacin hydrochloride in pharmaceutical tablet dosage form.

Keywords

Ciprofloxacin hydrochloride, UV Spectrophotometry, maximum absorbance, bulk, tablet