Asian Journal of Research In Chemistry
  • Year: 2012
  • Volume: 5
  • Issue: 3

Efficient Synthesis of Novel Pyrazolo thiazole derivatives and its Microbial Studies

  • Author:
  • K. Sivagurunathan, S. Raja Mohamed Kamil
  • Total Page Count: 4
  • Page Number: 401 to 404

Department of Chemistry, Islamiah College, Vaniyambadi -635 751, Tamil Nadu, India

*Corresponding Author E-mail: srmkamil@gmail.com

Online published on 7 February, 2013.

Abstract

Novel pyrazolo thiazole derivatives were synthesized by thioamide treated with various α-haloketones in ethanol. The structures of the newly synthesized compounds are characterized by 1HNMR, 13C NMR, LC-MS and screened for their antibacterial activity against Escherichia coli (ATTC-25992), Staphylococcus aureus (ATTC-25923), Pseudomonas aeruginosa (ATTC-27853) and Klebsiella pneumonia.

Keywords

Tert-butyl 6, 7-dihydro-1-methyl-3-thiocarbamoyl-1-H-pyrazolo [4, 3-c] pyridine-5(4H)carboxylate, Synthesis, Antibacterial activity